The awesomely powerful Megatron is, in many ways, a fallen hero. He rose up from the oppressed lower working castes of Kaon to become a champion in the region's illegal deathmatches, cast aside his designation of D-16 and took the legendary name Megatronus as his own, he called for an end to Cybertron's decrepit caste system and told the downtrodden that freedom of self-determination was the right of all sentient beings! But absolute power corrupts absolutely, and Megatron's Decepticon revolution, like many such movements, ended up becoming a whole new tyranny. Powerful, charismatic, violent, and full of rage for any who would stand in the way of his ambition and drive, Megatron brought Cybertron past the brink of destruction. Now he and his former brother-in-arms Optimus Prime fight on other worlds. Megatron will never forgive Optimus for "betraying" him, stealing from the Council the rank of Prime which was rightfully his. He has reserved for his old friend the greatest honor possible: glorious death at his hands. Megatron has been gone for three years, but now he's returned. He's brought the monstrous Dark Energon to Earth, and quite possibly left his sanity in space.
Megatron does not appear directly in Rescue Bots, nor do any of the other Decepticons. He is indirectly mentioned in Bumblebee to the Rescue, where it is mentioned that Bumblebee lost his voice box in the line of duty. As revealed in Transformers: Prime, Bumblebee's voice box was ripped out by Megatron.